张立国

张立国 男,1963年2月出生,辽宁建平人。1992年获天津大学化学工程博士学位后进入华东理工大学化学工程与工业化学博士后流动站工作,1994年初任副教授,1997年起任硕士生导师,中成药编委;国家发改委、科技部中药现代化项目评审专家,2006-2008年度国家科技进步奖(生物医药类)评审专家。国家新药评审委员会评审专家。2014年被聘为江西中医药大学兼职教授、博导;江西省中药制药工艺与装备工程技术研究中心常务副主任。承担多项国家攻关项目、科技支撑项目及企业重大合作项目、与国内大型制药企业有密切合作关系。主要从事天然产物及中药共性技术的研发与中药质量标准研究、中药新药研发工作,多项专利成果在企业转化,在科研成果产业化实施方面富有经验。

招生方向:
  (1) 分析化学(理学硕士)
  (2) 制药工程与技术(化学院工程硕士)
  电话021-64253045;email:zlgfyt@163.com
主要研究方向:
  (1) 天然产物(药物)质量分析与控制
  (2) 制药领域共性技术及其产业化
  (3) 中药新药研发

近期代表性成果:
  1 提取-吸附耦合富集丹酚酸B的制备方法及其装置,中国发明专利,ZL 200710039486.X
  2 丹酚酸B 结构修饰产物在制药中的应用,中国发明专利,ZL 200810040769.0
  3 挥发性成分提取装置及其提取方法,中国发明专利,ZL200810032234.9
  4 挥发性成分精馏-萃取耦合的提取装置及提取方法,ZL201010521943.0

5 Li-Guo Zhang, Xin Zhang, Li-Jun Ni,* Zhi-Bin Xue, Xin Gu, Shi-Xin Huang, Rapid identification of adulterated cow milk by non-linear pattern recognition methods based on near infrared spectroscopy , Food Chemistry, 2014,145:342-348

6  Li-Jun Ni, Xiao-Ling Xu, Li-Guo Zhang*, Wan-Zhong Shi, Quantitative evaluation of the in vitro effect and interactions of active fractions in Yaotongning-based formulae on prostaglandin E2 production, Journal of Ethnopharmacology, 2014,154:807-817

7 Zhang,L.G., Ouyang,X.W., Ni L.J., Shi, W.Z., Preparation and evaluation of the microcapsule containing volatile oil of Herba Schizonepetae by emulsion solvent
  diffusion method. Transactions of Tianjin University, 2014.20:103-111.
  8 Li-Guo Zhang, Xiao-Wen Ouyang, Ting-Ting Wu, Li-Jun Ni*, Wan-Zhong Shi, Quantitative evaluation of in vitro effects and interactions of active fractions in a Chinese medicinal formula (Yaotongning Capsule) on rat chondrocytes, Journal of Ethnopharmacology,DOI: 10.1016/j.jep.2014.07.011

9 Zhang Liguo, Fang Congying, Ouyang Xiaowen, Ni Lijun*, Simultaneous Determination of Saponins in Radix Glycyrrhizae, Notoginseng and Ginseng by High Performance Liquid Chromatography, Transactions of Tianjin University, 2013, 19(6): 430-435

10  L.G. Zhang, C.Zhang, L.J. Ni*, Y.J. Yang and C.M. Wang, Rectification extraction ofChinese herbs volatile oils and comparison with conventional steam distillation, Separation and Purification Technology,2011,77:261-268

11  L.J. Ni, L. G. Zhang*, J. Xie and J. Q. Luo, Pattern recognition of Chinese flue-cured tobaccos by an improved and simplified K- nearest neighbors classification algorithm on near infrared spectra,Anal. Chim. Acta,2009, 633: 43-50
  12  L.J. Ni, L. G. Zhang*, J. Hou, W. Z. Shi and M. L. Guo, A strategy for evaluating antipyretic efficacy of Chinese herbal medicines based on UV spectra fingerprints,Journal of Ethnopharmacology,2009, 124: 79-8...